Autoimmune diseases encompass a vast array of disorders in which an overactive immune system attacks its own cells and tissues leading to devastating consequences. In other words, your body damages itself. Researchers have identified greater than 100 different autoimmune diseases which are often chronic, debilitating and life threatening. Standard treatment in all cases is some form of immunosuppression to keep the immune system under control. Often the long term side effects of these treatments outweigh the benefits.
The National Institute of Health estimates that some 23.5 million Americans suffer from autoimmune diseases and it is one of the top 10 leading causes of death for women and children. Annual direct medical costs for care of autoimmune disease is in the range $100 billion dollars. It is well understood that understanding how to control or modulate the immune system is the key to controlling autoimmune disease.
In the field of stem cell science, mesenchymal stem cells (MSCs) are a cell type that offer immune modulation and growth support. Presently, there are greater than 15,000 scientific publications including several clinical trials in the field of mesenchymal stem cells demonstrating their beneficial therapeutic use. The majority of these publications focus on immune system control and growth. DaVinci Biosciences has also published articles demonstrating the potential of MSCs isolated from various tissue sources. We continue to research and develop strategies to treat autoimmune disease.
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