Arthritis involves the breakdown of articular cartilage as the result of disease and/or damage. Articular cartilage is found practically joints of the body such as hips, knees, shoulders, spine and pelvis. Arthritis occurs when this normally smooth gliding surface is no longer intact causing inflammation, pain, swelling and stiffness. More than 37 million Americans are affected by arthritis, a potentially debilitating condition. According to the Center of Disease Control, there are more than 100 forms of arthritis with yearly medical cost exceeding $128 billion dollars for treatments.
The standard of care for arthritis and sports injuries usually includes anti-inflammatories, analgesics, small biologics, physical therapy and commonly surgery. Alternative medicines include the use of glucosamine, chondroitin, methysulfonylmethane (MSM), and hyaluronic acid. Presently, stem cell therapies are increasingly used for arthritis and sports injuries. Many high profile sports figures such as Kobe Bryant and Rafael Nadal have had these procedures performed with excellent results which enable them to compete and win at the professional level. In the field of stem cells, mesenchymal stem cells (MSCs) are cell types that offer immune modulation (anti-inflammatory properties) and growth support. Presently, there are greater than 15,000 scientific publications including several clinical trials in the field of mesenchymal stem cells demonstrating their beneficial use and possible application to sports related injuries. DaVinci Biosciences has published in the field of MSCs demonstrating that these cells can easily be changed into cells that benefit arthritis and sports injuries. Therefore, we are developing effective strategies to treat arthritis and sports injuries.
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